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The results presented here indicate that EC neurons from mice genetically programmed to develop extensive Aβ and tau pathologies display alterations of intrinsic properties consistent with reduced membrane surface (atrophy) and show increased neuronal activity.
Although pediatric GIST consistently display alterations of SDHB protein expression, further molecular studies are needed to identify the crucial genes involved in their tumorigenesis.
Although pediatric GIST consistently display alterations of SDHB protein expression, further molecular studies are needed to identify the crucial genetic events involved in their tumorigenesis.
CD patients also typically display alterations of mesenteric fat depots, or 'creeping fat', suggesting that the local adipose tissue (AT) and adipokines may be involved in the pathogenesis of IBD.
Many basal-like breast cancer patient samples display alterations of established drivers of cancer development, including elevated expression of EGFR, p53 inactivating mutations and loss of expression of the tumor suppressor PTEN; however, their contribution to human basal-like breast cancer pathogenesis remains ill-defined.
Indeed, CSCs display alterations of DNA repair, due to the presence of cytoprotective properties (including telomerase activation and high expression of antiapoptotic factors) and express high levels of proteins belonging to the ABC membrane transporters family, involved in chemotherapeutic resistance [ 19].
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T1 generation of XB21RNAi/Kit do not display alteration of resistance to Xoo. (PPTX 3450 kb) Additional file 2: Table S1.
Production of ROS results in apoptosis and/or necrosis and can be used for selective targeting of tumor cells which possess higher oxidative stress level and display alteration of antioxidant enzymes (catalase, SOD) as compared to normal cells.
PE patients displayed alterations of plasma renin and angiotensin II in response to changes in dietary salt intake compatible with a primary increase in renal sodium reabsorption in hypertensive pregnancies.
At higher magnification, these neurons displayed alterations of their dendritic tree.
However, to the best of our knowledge, the present study is the first to reveal specific expressional changes of Cry2 in a mouse model of anxiety and co-morbid depression also displaying alterations of the behavioral circadian rhythm.
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