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In addition, we demonstrate that Fucα(1−2 Gal sugars are highly enriched in the developing OB and display a defined spatiotemporal organization that is regulated by FUT1.
In our own studies, we previously demonstrated that EMT-6 tumors display a defined level of hypoxia-driven uptake of [F]FAZA [ 47].
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Previous approaches targeted a binding pocket where derivatives of ligands displayed a defined structure-activity relationship.
Many of these endogenous molecules displayed a defined localization that correlated to specific tissue compartments (Fig. 4 C, D) while other compounds were more ubiquitously expressed throughout the tissue sample (Fig. 4 B, E).
Moreover, this interaction displays a defined upstream-downstream hierarchy of DSs, which can also be observed in Fig. 1.
In addition to the spatio-temporal dependence of the MECP2 expression, the brain contains a heterogeneous cell population, including both low MeCP2-expressing cells (MeCP2lo) and high MeCP2-expressing cells (MeCP2hi), displaying a defined distribution pattern.
Analysis of cell morphology over 30 s showed that ∼70% of control peptide and untreated cells displayed a defined leading edge comprising lamella and lamellipodium, whereas 50% of the β2-actinin peptide-treated cells had no definite leading edge, and a further 10% showed minimal lamellipodial extension.
After 3 5 h of cell starvation the impedance signal starts to display oscillations with a defined time period of a few minutes (5 12 min).
T3E genes were annotated as frameshift in two cases: (i) when several contiguous open reading frames displayed homology to a defined Rip gene sequence (thus resulting in the annotation of two or multiple gene fragments), and (ii) when the T3E gene sequence was located on a contig border (thus resulting in the annotation of a T3E gene fragment).
For example, many writers build and maintain a topical blog to develop their craft, as well as display passion and knowledge on a defined topic.
This spatiotemporal axis proposed by this conceptualization greatly improved our understanding of PD by displaying its clinicopathological sequence on a defined timetable.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com