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The test is successful if the cylinder, when examined under test pressure, does not display a defect described in § 180.205(i)(1) (ii) or (iii).
We have no explanation for the fact that so few mutants identified by us display a defect linked to Sonic hedgehog signaling, as was the case in the screens mentioned above.
Arabidopsis auxin receptor tir1 and response mutants, axr2, axr3 and slr1 not only display a defect in glucose induced change in root length, root hair elongation and lateral root production but also accentuate glucose induced increase in root growth randomization from vertical suggesting glucose effects on plant root growth and development are mediated by auxin signaling components.
mir-83 (n4638 ); mir-34 (gk437 ) double mutants display a defect in gonad morphogenesis.
D6-deficient macrophages display a defect in conversion to a resolution phase macrophage.
Tumor cells often display a defect in the DDR, associated with mutated or nonfunctional proteins involved in these pathways.
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This is illustrated by a mutant generated using dithitotreitol as an egress enhancer, which displays a defect in dithitotreitol induced egress but not in Ca2+ ionophore induced egress.
Wnt5a−/− mice also displayed a defect in (mid brain morphogenesis, including an impairment in midbrain elongation and a rounded ventricular cavity.
Additionally, when comparing HBeAg positive with HBeAg negative patients, we found that especially HBeAg-positive patients displayed a defect in the CpG-induced IFNα production (Fig. 6BD).
Deletion of C. neoformans STE12 displays a defect in filamentous growth during the monokaryotic fruiting process and no role has been previously noted regarding invasive growth [59], [60].
To the best of our knowledge this represents the first mammalian transgenic model displaying a defect in mitotic chromosome condensation and is also the first mouse model for impaired Mcph1-function.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com