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Patients with Crohn's ileitis (CDi) show a reduced antibacterial activity in their intestinal mucosal extracts and display a decreased expression of the Paneth cell alpha-defensins (DEFA5 and DEFA6) [13].
Additionally, class II MHC molecules that lack the cytoplasmic lysine of the β-chain display a decreased localization to the internal vesicles of multivesicular bodies, suggesting that ubiquitination is important as a signal for the inclusion of class II MHC in these internal vesicles [5], [6].
Also in contrast to the LB media cultures, cultures of S. typhimurium grown in LB-M9 salts media during spaceflight did not display a decreased LD50 value compared to ground controls using the same media (similar to the results with M9 media).
B-cell-specific G5PR knockout mice display a decreased number of splenic B cells.
In parallel, T-cell-specific G5PR knockout mice display a decreased number of thymocytes.
A negative sign that indicates TG mice display a decreased response for a particular parameter compared to NTG mice.
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In the present investigation, the ventilated animals displayed a decreased circulatory and renal function.
The mutant Cgt_ET1_F188Y displayed a decreased activity half-life of 28 min.
The TCBs displayed a decreased peak viscosity and an increased pasting temperature, compared with the MS alone.
Note that the rev3Δ control displays a decreased spontaneous base pair substitution mutation rate compared to wildtype.
Rather, the neutrophils in patients displayed a decreased β2-integrin signalling and/or adhesion capacity and a deficient intrinsic capacity to generate ROS.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com