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This is consistent with the reasoning that if hormone-dependent breast cancers respond to estradiol challenge with an increase in FDG uptake [16 18], then tumors dependent upon the ER pathway for growth should display a decline in FDG uptake as AI therapy lowers estradiol levels.
This is standard practice, but I agree that this adjustment should have been made more explicit in the technical appendix and excel file (also note that the raw series display a decline in top 1% wealth share between 1908 and 1920, but a sharp rise in the share of the next 9% (resulting into a significant increase in the top 10% share).
First, we examined whether aged cells display a decline in dealing with proteotoxic stress.
The estimated lactation curves in Figure 1 all display a decline in milk production post-peak.
This appears to correlate with the changes observed in RTE of older mice, which display a decline in proliferation and activation [ 7, 14].
In contrast, the HIV-1, CYDV, and RABV data sets did not display a decline in the estimate of ti/ tv over time, with estimates for the reduced-age data that were in the range of those obtained with random subsamples (Additional file 2: Table S2 and Additional file 5: Table S4).
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We therefore attempted to determine whether mutant mice displayed a decline in mental faculties.
High quality spermatozoa selected in discontinuous Percoll gradients displayed a decline in both vitality and motility after exposure to RF-EMR in a dose- dependent manner.
In this regard, both H3R−/− and C57BL/6 displayed a decline in body temperature starting from day 5 and no significant difference was observed between groups (Fig 1C).
Both genes displayed a decline in expression as the seed coat matured, but PsLAR transcripts decreased significantly faster than PsANR transcript.
However, excluding a WT mouse that displayed a decline in movement leading up to food presentation suggested an interaction between time and genotype (effect of time: F1,13 = 19.302, P < 0.01; time × genotype: F1,13 = 4.525, P≤ 0.05).
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Justyna Jupowicz-Kozak
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