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While these pathways can be inserted into the model, we note that in the case of the NtA construct, synergy must occur completely through nascent branch targeting, suggesting nascent branch targeting may be the dominant displacement pathway for the full-length protein.
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Ortho-substituted PCBs, which do not bind to the AhR, disrupt the HPT axis through other mechanisms which may include increased glucuronidation through non AhR pathways, displacement of T4 from the binding protein transthyretin, and direct effects on TSH release from the pituitary (Brouwer et al. 1990; Khan et al. 2002; van Birgelen et al. 1992 , 1995.
This change in localization appears to be a forward displacement within the secretory pathway, as GeaA1 is, in part, redistributed towards the apical plasma membrane, where exocytic carriers are preferentially delivered.
We compared our results using the displacement method for the FS pathway to those for other cellulosic ethanol pathways in our previous work [ 20].
Commonly used thermal EOR processes for the recovery of heavy oil such as steam flooding, CSS, conventional ISC, etc., uses vertical injection and vertical production (VIVP) wells, which operations are long-distance displacement, as the mobilised oil pathway to the production well is hundreds of metres.
Uptake by the displacement mechanism is a minor pathway compared to the shuttle mechanism.
Connectors are the gateway to the intraluminal pathway and studies link positive displacement, negative displacement, and split septum connectors to CR-BSI.
Moreover, they demonstrated that every functional displacement in the TAMD-generated pathways of each protein could be characterized by a few low-frequency normal modes.
The few exceptions that violate the otherwise good congruency between TCGs and 16S rRNA subtree regions point strongly to instances of whole-pathway trp-operon displacement.
The SDSA pathway is characterized by displacement of the extended primer from the D-loop, supposedly due to helicase action.
Nevertheless, the kinetic pathway of the obligatory displacement model fits the experimental data well, indicating that this model can explain synergy.
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