Similar(60)
Since the level of expression of these Rabs were unaltered by the depletion of Rab35 and MICAL-L1 (Fig. 3H,I, Fig. 4H,I, Fig. 5H,I), the Rab8, Rab13, and Rab36 in the Rab35-depleted or MICAL-L1-depleted PC12 cells were likely to have been dispersed from the perinuclear compartments into the cytosol or other membrane compartments.
Owing to such diverse and indispensable roles, Hsp70 is among the most highly conserved proteins, and many eukaryotic and prokaryotic genomes encode multiple Hsp70s: for example, humans have 13 Hsp70s dispersed among the cellular compartments for various roles.
Although PPAR γ was located in the nucleus in control cells, it was dispersed in the cytosolic compartment in TRAIL-treated cells.
A clear indication of RanGTP gradient collapse is the mislocalization of Ran from predominantly nuclear to being dispersed across the nucleocytoplasmic compartment.
While intense cell border NIS protein was evident in the tRAH-treated MCF-7 cells (arrows, left panel, Figure 1C) and sparsely located in the perinuclear area, it was not apparent in the MCF-7/PI3K p110αcellscells, where NIS appeared dispersed throughout the intracellular compartment (right panel, Figure 1C).
C2-ceramide dispersed the Stx6-positive sub-compartment and prevented insulin-responsive re-exocytosis of internalized GLUT4 myc, even under conditions not affecting insulin-stimulated signaling towards Akt.
Overall distribution of the protein inside the cells was compartmentalized but within each compartment, the calmyrin label was dispersed randomly.
The Turbofect™ solution (102 μl) was added to the luminal compartment in droplets that were dispersed throughout the wells, and the cells were cultured for 48 h in an incubator at 37°C with 5%CO2/95%% air.
Immuno-EM analysis of latrunculin-treated, HIV-infected MDMs demonstrated that HIV and immature budding particles were still found in intracellular compartments, although the IPMCs appeared more dispersed throughout the cells (Additional file 10).
A family of distinct ZnO morphologies – hollow, compartmented, core shell and full solid ZnO spheres, dispersed or interconnected – is obtained by a simple hydrothermal route, in the presence of the starch biopolymer.
Also, because they employ a digital gold signal that can be unambiguously identified, all the signal over a compartment can be collected even if it is low and widely dispersed.
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