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An intriguing alternative is to deploy a topographically dispersed array of miniaturized microphone pickups, linked by electronic circuitry, that quantifies the amplitude, classifies the nature of the sound – or absence of it – and displays an acoustic map of the structural or functional abnormalities that gave rise to that distribution of spontaneously generated sonic energy.
It consists of a pair of tubulin-based structures, called centrioles, encased in a dense, non-membranous, multi-protein cloud called the pericentriolar matrix (PCM), which is further surrounded by a dispersed array of proteins termed centriolar satellites (Bettencourt-Dias, 2013).
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Dense chromatin is methylated more efficiently by PRC2 than dispersed arrays.
The linker section of FCHO1, but neither the EFC domain nor μHD, also repatterns the bulky clathrin in MCF-7 cells to more regularly dispersed arrays.
An approach that partially tackles this problem is presented in [11] and relies on dispersed microphone arrays in order to get TDOA measurements related to two or more directional sources.
Adherent cells are dispersed over the array as suspension and allowed to adhere for a short period, commonly 5 to 15 minutes before unadhered cells, unable to make permanent contact onto the array background during the initial adherence incubation, are washed off.
Illumina BeadChips® have an entirely unique layout of 50 base pairs long oligonucleotides synthesised in a separate procedure and attached covalently to silica beads, which are randomly dispersed over the array so that they each lie in an unique well [ 4].
For experiments on the four well array plates, 2.5 × 10^6 cells in 4.5 ml of medium was added carefully to any corner of a single well, while avoiding application of cells directly onto the printed array surface and dispersed uniformly over the whole array surface.
Compared to NT arrays, dispersed NT powders showed high quality, and thus, the dimension and phase of NTs could be stabilized during high-temperature crystallization, as will be discussed in the next section.
It must be noted that short TCAST arrays dispersed along the assembled genome are evidently below the detection level by FISH.
The FokI, AluI and HinfI satellite families show dispersed localization in smaller arrays with different array sizes among chromosomes, preferentially in the intercalary heterochromatin and in terminal chromosome regions, respectively.
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