Mr Ash concludes that, paradoxically, "Belka has done such a good job, that he may well now be dispensable from a market perspective".
And in many ways I felt that investor had deemed me dispensable from the founding team.
In the peak hour, the routing control can lead to significant improvements in TTS and fuel economy, while a relatively small improvement in emission reduction is achieved; in the off-peak hour, however, it is opposite, which indicates that routing is possibly dispensable from the aspect of improving traffic efficiency, but is required from the aspect of emission reduction.
We find that unplugged/MuSK activity is dispensable from this time point until the 15-somite stage (∼16 hpf), and becomes essential by the 20-somite stages (∼19 hfp, in segments 11 15) to initiate AChR prepatterning.
LISP1, which appears to be specific to the Plasmodium genus, is important for parasite egress from hepatocytes but dispensable for egress from erythrocytes.
To understand the impact of natural variation on shoot stem cell maintenance, we analysed 28 wild-type Arabidopsis accessions from around the world and show that ZLL function is essential for stem cell maintenance in accessions mainly originating from Germany, but is dispensable for accessions from other regions.
Complicating matters further, it has been reported that longevity from sgk-1 RNAi also requires daf-16 (Hertweck et al., 2004), whereas daf-16 is dispensable for longevity from rict-1 RNAi or rapamycin (Robida-Stubbs et al., 2012).
Interestingly, although we found that RIP140 was recruited with ERα on the Myc enhancer, Myc expression was unaltered in both RIP140 KO and RIP140 Tg mammary tissues, indicating that either this site is not regulating Myc transcription or that RIP140 binding is dispensable for regulation from this site.
Structures of Spt16-NTD, the one domain that is dispensable for viability, from both S. cerevisiae and S. pombe have recently been solved by X-ray crystallography, revealing a motif that is structurally similar to bacterial aminopeptidases (Stuwe et al. 2008; VanDemark et al. 2008).
Jackson, as the story goes, was a pimp, and he filled twenty ships with England's most dispensable women, from the slums of Liverpool, Southampton, and London, but one or two of the ships got lost or sank en route; for expediency's sake, he then sent for replacements from the British West Indies.
List of 2,124 proteins contributing to the dispensable genome from a total of 5,999 genes.
