Sentence examples for disparate tissue from inspiring English sources

The multiple disparate tissue types that give rise to pediatric genitourinary cancers may help explain the dramatic differences in tumor development, physiology, and response to therapy seen in this complex family of malignancies.

In order to determine whether these effects were specific to Molt-4 cells, two cell lines of disparate tissue origin were analyzed, the breast cancer cell line MDA-MB-231 and the prostate cancer cell line PC-3.

There is a combination of similar and disparate tissue and temporal expression for these five actins (Krause et al. 1989; Avery 1993; MacQueen et al. 2005; Willis et al. 2006).

Though significant intra-individual telomere length correlation between disparate tissue types has been observed in healthy subjects [ 8- 13], few studies involving subjects with disease have evaluated telomere length in multiple tissues.

Thus, it was somewhat surprising when two independent studies, utilizing gene profiles identified from very disparate tissue samples, reported that ECM proteins associated with the fibrotic response, including fibronectin, collagens I, III, and VI, biglycan, fibulin 2, SPARC, and connective tissue growth factor were associated with improved survival [ 10, 14].

The same architecture can be found in a number of disparate tissues and may actually be the prevalent one on a whole-body scale.

Previous studies in sheep, humans, and genetically modified mice have pointed to inflammatory conditions as a cofactor enabling prion replication in disparate tissues, including liver, pancreas, skeletal muscle, mammary gland, and kidney [11], [25], [8].

Our results indicate that DS can be interpreted as segmental progeria, which affects at least two disparate tissues.

A close relationship between replicates and among tissues of similar origin was observed, whereas great variability in relation to disparate tissues was verified (Additional file 1: Figure S1c).

Interestingly, many putative CSC markers not only appear to mark CSCs from disparate tissues but also appear to overlap significantly with normal stem cell markers (Table 1).

The first principal component (PC1) explains nearly 80% of the expression variance in samples and displays a large separation between liver and brain tissues signifying substantial transcriptomic differences between these disparate tissues.