Bootstrap support for branching of many of the more disparate sequences was low.
Previous work by Reid et al. [ 32] included geographically (and taxonomically) disparate sequences from T. minimus individuals from California, Nevada, Utah, Wyoming and Washington and clearly showed that T. alpinus is nested with western segments of T. minimus scrutator.
In contrast, no similar structural information has been hitherto gathered for HIV-2, especially in the light of its disparate V3 sequence, lower resistance to neutralization and tendency for CD4 independence.
Indeed, we find affinity for disparate DNA sequences varies less than 3-fold for the homeodomain isolated from the Drosophila Hox protein Ultrabithorax Ia (UbxHD), whereas for the full-length protein (UbxIa) affinity differs by more than 10-fold.
Despite widely disparate DNA sequences, Burnett thinks the two viruses could have shared a common ancestor, because key parts of individual proteins are resemble each other in both species.
Herein, we report a class of slightly larger peptides (up to 34 amino acids long) that contain widely disparate peptide sequences, resulting in a broad range of cellular binding and radioisotope uptake properties.
31 Phylogenies of such disparate OR sequences across genomes were retained mainly to impart this important result of non-clustering of ORs from few genomes, for instance human and Drosophila ORs.
Based on the observation of chemical shift averaging and narrow backbone amide resonances, it has been suggested that the linker L12 is conformationally flexible in order to enable the interaction of this binding surface of the KIX domain with a variety of disparate ligand sequences, while in complex with MLL, the conformational flexibility is reduced.
We show, using five distinct chain architectures including two triblock terpolymer sequences and three disparate diblock terpolymer sequences, that the manipulation of the "C" segment distribution through statistical copolymerization is a simple tool that polymer chemists may use to tune the stable morphology at constant chemical composition.
For neighboring unique promoters with similar motifs, but not for those with disparate motifs, promoter sequence similarity is highly correlated with gene sequence similarity (r = 0.70, versus r = 0.07), indicating that not just the known motifs but the sequences of the promoter region in general are highly related.
