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New classes of snoRNAs have also been identified and shown to directly participate in disparate cellular processes from pre-mRNA splicing to chromatin decondensation (Jady et al., 2012; Schubert et al., 2012; Yin et al., 2012).
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A range of studies present a complex picture in which KLF/SP genes can be singly or combinatorially involved in temporally and spatially disparate cellular and developmental processes.
As their profiles and functions are disparate in many cellular processes like the EMT and its reversal, the MET, the alternation of Fra-1 and c-Fos expression may determine reversible switches between proliferative and invasive phenotypes and manifest the plasticity of tumor cells in aggressive carcinomas.
The challenge was not to identify another ?metastasis-relevant? gene but to connect and articulate seemingly disparate genes, gene clusters, and cellular processes that bear on cancer metastasis.
In fact, these are potentially noncomparable measures arising from distinct cellular processes; therefore, greater clarity is called for when examining and reporting these disparate measures.
Thermodynamics of Cellular Processes.
A picture is emerging of STAM/EAST/Hbp proteins acting as integrators of thus far mechanistically disparate cellular signalling events.
Systematic genetic interaction studies have illuminated many cellular processes.
Independent cellular processes for hippocampal memory consolidation and reconsolidation.
Some of it may be just a nonfunctional byproduct of other cellular processes.
"It turned out to be absolutely crucial for the regulation of cellular processes," he said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com