Exact(6)
This study selected 36 disparate compounds across seven classes of TOrCs for analysis using a single extraction method and short analysis time.
Microdialysis Techniques in Neuroscience focuses on the practical aspects of microdialysis in animal and human, highlighting current technical limitations and providing a vision of what is yet to come for the determination of the most disparate compounds in the brain.
Again, these findings illustrate that the PC12 model can incorporate factors such as protein binding that are critical issues for the developmental neurotoxicity of disparate compounds in vivo.
Although young animals are far more susceptible than adults to organophosphate-induced growth inhibition and lethality, there is a wide range over which disparate compounds elicit such effects.
However, again, the main point is that a relatively facile set of markers in PC12 cells can detect adverse effects on neural cell acquisition across a wide array of disparate compounds in a short period of time.
First, we examined TBARS as an index of lipid peroxidation with the idea that oxidative stress and resultant membrane damage could represent a common mechanism underlying the neurotoxicant actions of otherwise disparate compounds, especially in light of the prominence of oxidative stress in the noncholinesterase-related targets of organophosphates (Gupta 2004).
Similar(54)
The common aspect of drug action from this disparate group of compounds is generalized anti-inflammatory activity in the AD animal model.
Further, many kinds of volatile compounds with disparate structures can bind to the same odorant binding protein [ 40].
A panel of 9 compounds with disparate in vivo clearance profiles was assessed in the system and a strong in vitro-in vivo correlation was observed for eight of the nine compounds, indicating good predictivity of hepatic clearance (Dash et al., 2009).
One sign of "Arcadia"'s greatness is how assuredly it blends its disparate chemicals, creating a compound of most peculiar properties.
The similar but more disparate product distributions with compound 5 favor the conclusion that substrate modifications are primarily uncovering occult reactivities rather than markedly altering substrate-binding trajectories.
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