Despite being disorganized, gradual development of this system was anticipated by the NHC.
For instance, artificially extending the half-life of the Hes7 transcription factor by ∼8 min severely disorganizes embryonic development in mice (Hirata et al., 2004).
Despite the warm waters, Gordon did not strengthen that day as strong upper-tropospheric shear hindered development, disorganized the upper level circulation, and reduced its winds to 40 mph (65 km/h).
On October 1 it entered the eastern Pacific Ocean, and continuing westward it developed an area of persistent convection on October 5. Initially the system was disorganized, although gradual development was expected as conditions in the upper-levels of the atmosphere were expected to become more favorable.
Castori 2013 reported that diabetes during pregnancy disorganized placental and fetal development.
NHERF1-deficient mice have intestinal brush border structural defects and we report here that they also have disorganized ependymal cilia with development of non-obstructive hydrocephalus.
Role reversal, as observed in parental representations and behavior, has been highlighted as a key risk factor for the development of disorganized attachment relationships (George & Solomon, 2008; Lyons-Ruth, 2003).
Mice deficient in LT βR, its ligands, or downstream signal molecule nuclear factor- κB-inducing kinase (Nik) caused defects of thymic medulla development including disorganized medullary architecture, significant reduction in overall mTECs, and retention of T cell maturation with autoimmune disease [ 23– 25].
These results suggested that TBT might perturb the proliferation and differentiation of chondrocytes, and disturb calcium homeostasis, thus disorganizing craniofacial skeletal development.
