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The need to develop new approaches for treatment of these disorders arises from the fact that conventional therapeutic strategies face many obstacles and limitations.
Symptom burden in common headache disorders arises from pain, and, in migraine, additionally from nausea, vomiting and photo- and/or phonophobia.
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Imprinted disorders arise from inappropriate genetic alterations within imprinted domains.
Hearing and balance disorders arise predominantly from inner-ear dysfunction.
Our overarching focus is to model how brain disorders arise and to develop disease-specific treatments.
These cells offer great hope as a preliminary tool for understanding how certain disorders arise and discovering more advanced therapeutics.
But Intellia has a deal with pharmaceutical giant Novartis to focus on cancer and genetic disorders arising in blood cells.
Baker, L.A., Allis, C.D. & Wang, G.G. PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks.
Duchenne and Becker muscular dystrophies are allelic disorders arising from mutations in the dystrophin gene.
Polycythemia vera (PV), essential thrombocythemia (ET), and myeloid metaplasia with myelofibrosis (MMM) are clonal disorders arising from hematopoietic progenitors.
Memory disorders arising in patients with compromised cognitive control systems are often traceable to a failure of strategic guidance, evaluation and use of memory8.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com