Because CNVs have been associated with many diseases, from cancer to autoimmune disease to neuropsychiatric disorders, understanding how they cause deleterious effects is important.
Because of the strong association between hepatic fat accumulation and metabolic syndrome disorders, understanding how genetic factors influence the way in which the liver responds to increased dietary fat levels is critical.
The main course objectives include: Understanding the anatomical and physiologic basis of neurological disorders Understanding basic concepts of neurological disorders, for example: neuropathic pain, seizures, movement disorders, stroke, voluntary muscle and neuromuscular disorders, dementia, and so on.
By characterizing endophenotypes, or "upstream" phenotypes that do not always result in the "downstream" disorder, progress may be made in both deconstructing the etiologies of complex psychiatric disorders and understanding the genetic and evolutionary basis for variation in non-disordered individuals [ 4].
13 Furthermore, we argue that it is very difficult to understand the changing impact of educational credentials on psychiatric disorders without understanding the significance and role of education in the broader political and labour market context.
One of the priorities is to move from simply describing psychiatric disorders to understanding how they develop.
17 Given the public health importance of the increasing rates of both obesity and common mental disorder, 18 19 understanding the nature of the association between these two conditions is crucial and could potentially inform prevention and treatment.
GABAC receptors, which are a subfamily of GABAA receptors, are members of the Cys-loop superfamily of ligand-gated ion channels (LGICs), an important group of receptors involved in rapid synaptic transmission and whose malfunction can result in a variety of neurological disorders; hence, understanding their mechanism of action is of considerable pharmacological interest.
Factors involved in regulating myelination during development are often also involved in demyelinating disorders, and understanding their actions is crucial to designing treatments or therapies (Setoguchi et al., 2001; Armstrong et al., 2002; Liu et al., 2008b; Zhang et al., 2009; Cate et al., 2010).
These and other areas of research hold great promise for understanding disorders with significant interactions between mind and body.
