Sentence examples for disordered expression from inspiring English sources

Beckwith-Wiedemann syndrome (BWS), a congenital overgrowth disorder with variable expressivity and a predisposition to tumorigenesis, results from disordered expression and/or function of imprinted genes at chromosome 11p15.5.

In this respect, the low and disordered expression of fibronectin in periostin−/− hair follicle shown in Figure 9A suggests the degradation of this architecture.

They, instead, display either trivial or highly disordered expression trajectories characterized by uniformly distributed and spike-like expression domains (see Figures S3A S3D).

Disordered expression of proteins in these processes may cause male sterility [ 16, 19].

In contrast to the elusive function of mammalian endo-siRNAs, somatic miRNAs in mammals regulate numerous biological processes, and their disordered expression has been linked to human diseases.

The altered expression of a miRNA gene, due to mutation or epigenetic event, might in turn result in the disordered expression of the modules enriched in its targets [ 20, 18].

Cancer is fundamentally a disease of disordered gene expression.

These results suggest that the disordered gene expression in carbohydrate metabolism and energy germination resulted in reduced accumulation of total sugars, a lack of starch and other substances synthesis in the MT pollen grains, thus providing critical information augmenting our understanding of male sterility.

Our hypothesis was that the metastatic cancer phenotype is characterised by a higher level of randomness in the sense of a more disordered local gene expression correlation pattern.

Researchers also provided evidence for the fact that proteins which are entirely disordered (80%to100%0% disordered residue) with high level of expression can bypass the route of rapid degradation to successfully carry out their functions [ 19].

Avoiding potentially disordered segments in protein expression constructs can increase expression, foldability, and stability of the expressed protein.