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To diagnose PTSD, the Clinician-Administered PTSD Scale (CAPS) [ 43] was administered by a trained clinician and the diagnosis of major depressive disorder was determined using the Patient Health Questionnaire (PHQ-9)[ 44] and the psychiatric interview according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria [ 6].
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The prevalence, type and mental health correlates of substance use disorders were determined using a diagnostic interview and questionnaire.
If the main disorder differed between the two eyes the disorder for the person was determined using the following criteria: The disorder most amenable to treatment was selected.
The diagnosis of dementia was determined in consensus with fourth edition of the The Diagnostic and Statistical Manual of Mental Disorders [ 16] and the subtype of AD was determined using the NINCDS-ADRDA criteria [ 17].
Diagnostic status was determined using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) [45] sections for mood disorders, psychotic disorders, and substance abuse disorders, and chart review.
Peptide binding was determined using ELISA.
Iodine uptake was determined using radioactive iodine.
Signal intensity was determined using GeneChip Operating Software 1.4.
Proteasome activity was determined using fluorescence assays.
Survival was determined using Kaplan Meier test.
Protein concentration was determined using a BCA Assay Kit Piercee).
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