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The study of 16p12.1 microdeletions presents an interesting case study of the previously underappreciated complexity of genetic disorder pathogenesis.
Serotonin secreted from the dorsal raphe nuclei is implicated in both the control of mood and anxiety disorder pathogenesis and sleep cycles [ 38].
While considerable efforts have been made to identify the mutations that characterize this disorder, pathogenesis remains a work in progress with less than 100 patients described in current literature.
Using this panel of antigens and a sensitive, robust assay, no evidence of unusual immunoreactivity was detected in children with autism, providing evidence against a role of autoimmunity against several previously implicated proteins in autism spectrum disorder pathogenesis.
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Therefore, advanced drug delivery systems are to be developed for transport of potential biopharmaceuticals to treat CNS related disorders, pathogenesis, and neoplasticity.
Indeed, for such disorders, pathogenesis is usually slow and, at least in the case of autoimmunity, the onset of symptoms and formal diagnosis can take place several years after autoantibodies are first detectable in serum.
As an autoimmune disorder, the pathogenesis of GD remains elusive.
As a complex and heterogeneous disorder, the pathogenesis of PCOS has remained largely unknown until now.
Little is known about the molecular mechanisms or genetic disorder of pathogenesis of EPD.
It is a chronic, inflammatory, non-infectious disorder, whose pathogenesis is still not fully elucidated.
OSAHS is a common chronic sleep disorder, the pathogenesis of which is uncertain and likely to be a multifactorial process that includes sympathetic excitation, inflammation, and oxidative stress.
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CEO of Professional Science Editing for Scientists @ prosciediting.com