In the case of combination product (cleaner-disinfectant) application, these procedures can not be followed.
In order to avoid infection or diminish its incidences in bone allograft, strategies like careful donor selection, aseptic processing, proper use of disinfectants, and application of sterilization procedure with bacterial cultures need to be taken [ 23].
A combination of cleaning chemicals and disinfectants, temperatures, times, application methods and sequences are used to reduce soiling, including microorganisms, to a level that is not harmful to product quality and safety.
The application of disinfectant thermo-nebulised into the air of laying hen houses to reduce airborne microorganisms was evaluated with emphasis on its effect on Mycoplasma gallisepticum.
However, each disinfectant has its own application objectives, and disinfectant-related studies have not been adequately performed for Brucella.
Cleaning with detergent solution reduced microbial burden by 35% while application of disinfectant yielded 90% reduction.
The treatment of hands and forearms has been described to be equally effective in 1.5 min [ 13], but will certainly require a larger volume of disinfectant for the same application time.
We found that the device was effective in reducing contamination in sites not easily amenable to manual application of disinfectant (e.g., the undersurface of bedside tables) and on portable equipment.
Venkitanarayan et al. [ 21] have investigated the effectiveness of super-oxidized water against Escherichia coli O157: H7, Salmonella enteritidis and Listeria monocytogenes and reported that electrolyzed water can be used as an effective disinfectant provided that standardized application methods are used.
After routine hospital cleaning of the rooms of MRSA carriers, 18% of sites under the edges of bedside tables (i.e., a frequently touched site not easily amenable to manual application of disinfectant) were contaminated with MRSA, versus 0% after Tru-D (P < 0.001).
