Your English writing platform
Discover LudwigExact(3)
The characteristics exhibited by PDD curves obtained using Monte Carlo simulation can be explained based on the lateral electronic disequilibrium effect that is more important for small fields.
Figure 6 shows that the PDD, or the absorbed dose, is increased at about 10, 5 and 3% respectively to 1×1, 2×2 and 10×10 cm2 field sizes due to lateral electronic disequilibrium effect that is more important for small fields.
Studies that simply report SNPs [ 15] in association with disease (and hence are likely to represent merely a linkage disequilibrium effect), but with no additional evidence of direct functional involvement of the variants in question, are also not included.
Similar(57)
More notably, the reliability does not monotonically increase with the number of redundant cells for the thermal disequilibrium effects.
Even high-density mapping with common SNPs has in most cases not been able to distinguish an association signal due to direct association with disease risk from an indirect association signal due to linkage disequilibrium effects.
Finally, to avoid linkage disequilibrium effects, putative cis- trans-acting regulators (using a conventional 0.05 p-value cutoff) were excluded and regulator-target pairs residing on the same chromosome were removed.
This evidence strongly suggests that further studies of the MHC for AS-susceptibility genes other than B27 are likely to be quite fruitful, although the sample sizes required to differentiate linkage disequilibrium effects from true association are substantial.
Due to linkage disequilibrium, the effect of a QTL may be spread over a number of neighboring SNPs.
Although linkage does not seem to strongly affect genotypic disequilibrium, the effect of the presence or absence of ORS337 was assessed in the statistical tests to avoid any misconclusion.
The possible differences in selection of cases and controls, patterns of linkage disequilibrium and effects of gene-gene interactions may also account for the inconsistent findings.
Possible reasons for failure of replication for some loci include inadequate study power, differences in allele frequency, linkage disequilibrium structure or effect size between populations.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com