The challenge is to disentangle the artifactual consequences of participation bias from genuine aetiological factors.
The challenge remains to disentangle the complexities of racial/ethnic differences in screening, treatment, biological and environmental factors that contribute to differences in risk across groups.
Identification of the role of different component providing salt stress and the cross talks between these components will be a future challenge to disentangle the complete genome network of rice providing salinity tolerance.
Both processes happen simultaneously so it is challenging to disentangle the effects of assimilation change in preferences from those of adaptation adjustment in fertility behavior due to economic opportunities and constraints (Lindstrom and Saucedo 2002).
15 Finally, it was challenging to disentangle the causal conundrum between depressive symptomatology and frailty with the currently available literature, which is observational in nature.
In pharmacoepidemiological studies, it is always a challenge to disentangle the effects of the medication from the effects of the underlying disease (confounding by indication).
Little is established about the role of hyperestrogenism in sSCAx males as it is often challenging to disentangle the effects of aberrant sex hormone levels from other concomitant genetic abnormalities.
Given the experimental challenge to disentangle the division of function among the retroposed and parental copy as well as distinguishing between subfunctionalization and neofunctionalization, we used an alternative approach to test the contribution of retroposition to the demasculinization of the Drosophila X-chromosome.
However, let us remind that boreal conifers such as P. glauca have undergone population expansion since the last glacial maximum, making it a challenge to disentangle the effects of selection from demographic effects (e.g., Namroud et al. 2010; Pavy et al. 2012b).
Measures of IOP fluctuation have included a wide range of quantities - peak, trough, variance, and range, etc. [ 13] However, since subjects with high mean IOP often show large IOP variability over time, it is challenging to disentangle the effect of fluctuation from mean IOP.
