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Other than cattle rustling, there are other factors such as droughts and diseases that influence the decision to migrate.
Using the PBPK model to assess the effects of elevated cytokine levels on suppression of CYP450 enzymes was a viable approach for risk assessment for blinatumomab, and potentially for other therapeutics or diseases that influence cytokine levels.
The exclusion criteria were: 1) systemic/endocrine diseases that influence bone metabolism, e.g., osteoporosis, hyperparathyroidism, Paget's disease, and renal osteodystrophy; 2) topical conditions that may affect bone quantity and quality at anterior maxilla, e.g., moderate to severe periodontal disease, cyst, neoplasm, prior trauma or surgery.
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Given that SLE is a systemic disease that influences multiple organs, Lee and colleagues [ 1] emphasized the importance of assessing biological and cellular abnormalities associated with SLE other than those related to the immune response.
Klyscz et al. [ 21] described how the experience of CVI patients changed from a primarily cosmetic problem (CVI stage I) to a rather complex disease that influenced all aspects of life in patients with CVI stage III.
Despite these important findings in immune response, because SLE is a systemic disease that influences multiple organs, it is also important to clarify other biological or cellular functional abnormalities relevant to SLE clinical manifestations other than immunological response abnormality.
Another weakness of the present study is the lack of systematically collected clinical information concerning smoking habits, airway symptoms, and pulmonary diseases that might influence mucociliary clearance.
Patients included had to be at least 18 years old, both systemically and periodontally healthy with good oral hygiene; patients who were heavy smokers or bore systemic diseases that could influence bone turnover/wound healing were excluded.
Generalized bone disease or other diseases that could influence bone properties were not diagnosed in any of the horses.
Osteoporosis (OP) and osteoarthritis (OA) are two common diseases that severely influence quality of life, especially for the elderly.
Patients with other chronic wasting diseases that could influence serum albumin levels or survival or those lacking complete data were excluded.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com