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Pharmacogenetics of auto-immune diseases is a complex field of application for this relatively new discipline, since we still have a partial knowledge of the biological mechanisms of the disease and of the drugs currently used to treat it.
It has been acknowledged that managing these diseases is a complex process and that both the economic and social burdens are significant [ 3].
Initiation and maintenance of angiogenesis in angiogenic diseases is a complex process requiring modulation of numerous pro- and anti-angiogenic molecules operating through complex intracellular signaling pathways.
Treatment of severe exfoliative skin diseases is a complex process that requires a multidisciplinary approach, but the most important decision is to direct the patient to a burn intensive care unit.
The interaction of miRNA and diseases is a complex web of multilevel interactions, given the fact that a miRNA regulates upto 50 or more diseases and miRNAs/diseases work in clusters.
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The researchers point out that motor neurone disease is a complex condition, there may be many genes involved, and that the animal work so far has only yielded one candidate gene.
Alzheimer (AD) disease is a complex neurodegenerative disease characterised by inflammation, neurotoxicity, oxidative stress, and reactive gliosis.
This disease is a complex, multifactorial chronic disorder in which a variety of pathophysiologic mechanisms lead to skeletal fragility.
Background & Aims: Celiac disease is a complex, immune-mediated disorder of the intestinal mucosa with a strong genetic component.
Adjusting to chronic disease is a complex process and one that, in the case of inflammatory bowel disease (IBD), has received very little attention.
This disease is a complex, age-related, and inherited optic neuropathy with characteristic slow progressive loss of retinal ganglion cells and excavation of the optic disc.
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