In other autoimmune diseases, doses of 20 mg (RA, PsA) [ 5, 6] and 30 mg (GPA) [ 8] were used in order to induce remission.
While this single activity may lead to suboptimal radiation doses in neuroendocrine tumors (NET) with advanced or bulky disease, dose escalation has been withheld due to concerns on potential tumor somatostatin receptor saturation with reduced efficacy of the added activity.
Only three variables, however, had a significant independent effect: lung disease, dose of prednisone and treatment with antimalarials at the study point, the latter showing a strongly protective effect.
In the case of patients with kidney disease, dose reductions are required in patients with a creatinine clearance (CrCl) of 30 to 50 mL/min because renal impairment prolongs the half-lives of NOACs, especially dabigatran.
The survey is conducted every trimester through a structured questionnaire to allow for data capture by each doctor and specific medical visits, patient demographics, week surveyed, type of disease, dose and amount prescribed (volume, formulation and dosage per diagnosis).
In addition, these studies used classifications of previous diabetes based solely on the clinical history and failed to control the analyses for confounding variables, which may greatly influence both hyperglycemia and mortality (e.g., degree of malnourishment, severity of disease, dose of carbohydrates infused, glycemic variability).
For patients with intermediate-risk or high-risk disease, doses up to 81.0 Gy provide improved disease control as assessed by prostate-specific antigen (PSA).
Reviewer access: http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi token=ftixhsoiemwgyfi&acc=GSE30070 Eastern Cooperative Oncology Group, partial response, stable disease, progressive disease *Relative dose intensity *Mean of relative dose intensities of cisplatin and fluorouracil.
With most infectious diseases, the dose of the germ matters: The more people are exposed to, the more likely they are to get sick, said Dr. William Schaffner, an infectious disease expert at Vanderbilt University.
Factors generally not associated with post-BMT QOL included disease diagnosis, dose of total body irradiation, presence of chronic graft-versus-host disease (GVHD), type of GVHD prophylaxis and extent of marrow graft match.
