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These characteristics make MSCs an ideal candidate cell type for tissue engineering efforts aiming to regenerate replacement tissues for diseased structures.
(2) The second pathway refers to the convergence of sensory inputs from normal and diseased structures to the same spinal interneuron located in the dorsal horn of the spinal cord.
(iv) Alterations in the ECM might cause or reflect derangements to the release of or diffusion of chemoattractants that activate neural progenitor cells and promote their migration toward diseased structures to try to 'rescue' degenerating motor neurons (61); alterations in the ECM might allow propagation of a maladapted process.
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The ease of isolation and expansion and the multipotential differentiation capacity, especially the chondrogenic differentiation property of MSCs, make MSCs the cell type of choice for articular cartilage tissue engineering that aims to replace and regenerate the diseased structure in joint diseases.
After a mathematical extension of the existing model for the theoretical description of the aerosol bolus dispersion, the behavior of particle pulses in diseased lung structures was simulated.
Regenerative endodontics are referred to as biologically based procedures which aim to replace diseased, damaged, or missing structures such as dentin, root structures, and cells of the pulp-dentin complex [ 4].
Auscultation also reveals the modification of sounds produced in the air tubes and sacs of the lungs during breathing when these structures are diseased.
By slightly modifying the fabrication process, more complex structures simulating diseased artery phantoms can be fabricated [ 78].
The ultrasonographic findings of the spleen, liver, gallbladder, caudal vena cava and portal vein in six healthy Holstein-Friesian calves from birth to 104 days of age serve as reference values for the examination of these anatomical structures in diseased calves.
Intra-articular administration of HA2700 and HA800 is widely used as a symptom-modifying treatment for knee OA, 14 15 and growing experimental and clinical evidence suggests that HA2700 and HA800 may also modify the structure of diseased joints and slow the rate of OA disease progression.
He warned against the dominance of pathologic anatomy the study of the structure of diseased tissue alone as such and stressed that the future of pathology would be physiologic pathology study of the functioning of the organism in the investigation of disease.
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