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Patients with significant valvular disease were excluded.
Patients with congenital heart disease were excluded.
Patients with cyanotic cardiac disease were excluded.
Subjects with severe pediatric disease were excluded.
Patients with chronic kidney disease were excluded.
Patients hospitalized in ICU for cardiac disease were excluded.
Patients with estrogen receptor negative disease were excluded from the analysis.
Patients with severe lung disease were excluded from the randomized Phase 3 trials.
Here, the two animals with cure/stable disease were excluded from the estimated delay time.
Patients with systemic rheumatic disease, a condylar fracture, or psychiatric disease were excluded.
Patients with prior heart failure, cor-pulmonale, pulmonary hypertension and valvular disease were excluded.
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