Sentence examples for disease replication from inspiring English sources

To gain insights into isolated/nonsyndromic USH2A retinopathy, we screened USH2A in 186 probands with recessive retinal disease and no hearing complaint in childhood (discovery cohort) and in 84 probands with recessive retinal disease (replication cohort).

Although genetic association studies in complex disease require replication before they can be accepted, our studies indicate that SNPs in TSHZ1 and TSHZ3 show genetic association with AD.

Given the association between HIV-induced central nervous system (CNS) disease and replication of HIV in immune-activated macrophages, CCR5 antagonists may attenuate CNS disease by modulating inflammatory signaling and by limiting viral replication.

Oxidative stress occurs secondarily to increased total lipid peroxidation and inadequate total antioxidant response and is related to severity of the disease and replication status of virus in hepatitis B infection.

Such "flip-flop" associations have been reported with increasing frequency as GWA scans are completed for many common diseases, and replication efforts are subsequently undertaken [50].

On the day of disease onset, replication-incompetent alternative splice variant-expressing adenoviruses were administered as a single dose of 1 × 107 plaque-forming units.

However, as is the case in severe liver diseases, this replication may become insufficient or exhausted and hepatic progenitor cells (HPCs) can be activated in an attempt to restore liver function.

In this report, human genetic association results from the literature are summarized with regard to replication, disease phenotype, and gene specific results; and organized in the context of a systematic disease ontology.

In vaccinated pigs, there was no evidence of disease or PCV2 replication following dual virus challenge.

In order to accomplish the goals of this study, it was necessary to study the same patient on two occasions at the same disease stage (biological replication) as well as to access technical reproducibility by examining samples from a completely independent patient cohort.

PURPOSE: To correlate tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) synthesis with histopathologic disease and virus replication within murine cytomegalovirus (MCMV -infected eyes during progression of MCMV -infectedd immunodeyesiency synduring(MAIDS).