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We did not include generic health measures including the Health Assessment Questionnaire, EuroQol, London Handicap Scale, Medical Outcomes Study Short Form-36 (SF-36), Disease Repercussion Profile, Sickness Impact Profile and WHOQol-BREF.
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The general instruments are applicable to any population, and are better suited to studies that seek to ascertain the disease's repercussion on HRQL, taking the general population as reference [ 8].
Motor impairment is the main manifestation of this disease, with repercussions regarding the biomechanics of the body [ 3, 4].
But one form of the disease has particular repercussions for women and their health and reproductive systems -- FGS.
Questionnaires specifically designed for the disease explore the repercussions of the most usual symptoms and side-effects, and are appropriate for comparing treatments or changes in patients.
The results will serve as the basis for appropriate genetic counseling to inform patients and their families about the disease and its repercussions, especially reproductive issues.
Patients' clinical condition and wellbeing deteriorate during the course of the disease, with enormous repercussions on their ability to perform daily activities, to work, to have an effective family and social life, and hence on their wellbeing [ 4- 6].
We analyzed neither the whole spectrum of nonadherence/nonpersistence nor its repercussion on disease activity and damage – clinical outcomes of treatment are affected not only by how long patients take their medication but also by how well; accordingly, adherence should have been defined and measured to characterize medication-taking behavior comprehensively.
Participating subjects were presented with a questionnaire in order to determine the knowledge they possessed on repercussions the disease might exert on their oral health, within the frame of our basic health zone, as well as risks encountered when receiving dental care in a state of uncontrolled disease.
The questions investigated here merit further evaluation, bearing in mind that this information may have important repercussions in disease surveillance and control.
Inadequate prescription of cholesterol-lowering drugs in patients with no history of cardiovascular disease may have negative repercussions for the patient as well as for the health care system.
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