Sentence examples for disease module from inspiring English sources

Taken together, Fig. 7 indicates that the tissue-specific disease module acts as an effective filter, aggregating the diseases genes with high GWAS significance and keeping less relevant genes apart from the disease module.

To test the significance of the observed disease module we assume that disease genes do not preferentially interact in the tissue-specific interactome.

Most important, we show that it is the integrity and the completeness of the expression of the disease module that determines disease manifestation in selected tissues.

Consequently, reducing the disease module to a specific tissue acts as a natural filtering procedure, automatically eliminating the functionally and potentially mechanistically less relevant disease genes.

Combining these observations, we arrive at a putative disease module for tauopathies consisting of nine genes that form a connected subgraph (Fig. 3G).

Meanwhile, network-based methods are becoming dominant since they well exploit a "disease module" principle in microRNA functional similarity networks.

In this paper we offer a disease module-based approach towards understanding the tissue specificity of human diseases.

For the common genes or proteins shared by diseases shown in the disease-module network, drugs designed for one of the disorders may also be used for the other.

Because of the need for a more appropriate measurement, the PedsQL™ End Stage Renal Disease Module [ 3] was developed as a PedsQL™ disease-specific module.

Similarly, medium negative correlations were also found between two EQ-i subscales (Interpersonal relationship: r = −.39, p ≤ .05; Happiness: r = −.35, p ≤ .05) and performance on one of the other modules, the Biology and Epidemiology Disease module.

How to cite this article: Kitsak, M. et al. Tissue Specificity of Human Disease Module.