Sentence examples for disease modification from inspiring English sources

Reduction of Hcy to normal levels therefore presents a new approach for disease modification.

The era of disease modification as a therapeutic option for Alzheimer's disease (AD) is upon us.

Incorporation of a biomarker into clinical trials will support the claim for disease modification.

TET2 appears to be mutated in primary human samples in aggressive types of SM, suggesting a possible role in disease modification.

The ability of sitagliptin to enhance islet cell function may offer insight into the potential for disease modification.

The concept of disease modification in Alzheimer's disease is controversial and the design of these trials raises many questions.

Disease modification of epilepsy refers to the alleviation of epileptogenesis or comorbidities after genetic or acquired epileptogenic brain insults.

Disease modification can be defined as treatments or interventions that affect the underlying pathophysiology of the disease and have a beneficial outcome on the course of AD.

The chapter also concentrates on the amyloid lowering approaches that will test the "amyloid hypothesis" and offer a real prospect of disease modification.

A third axis of information supportive of disease modification is derived from observation of the effect of treatment in animal models of AD.

Each of these has shortcomings, and by themselves trial designs are not likely to provide sufficient information to conclusively prove that disease modification has occurred.