Brain organoids: a next step for humanized Alzheimer's disease models?
Alzheimer's Disease: Models of Computation and Analysis of EEGs -- 12.
Domanskyi, A. et al. Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models.
Transgenic primates could also prove extremely helpful as disease models for ALS and Alzheimer's.
Musunuru, K. Genome editing of human pluripotent stem cells to generate human cellular disease models.
Sarkar, S. et al. Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
Sandoe, J. & Eggan, K. Opportunities and challenges of pluripotent stem cell neurodegenerative disease models.
Comprehensive pre-clinical studies aimed at establishing effectiveness of TAS2R agonists in disease models are lacking.
Day, M. et al. Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models.
Further development into disease models is progressing for lung equivalents5 and for liver equivalents6,7,8.
Cool, silent, aloof, this Freud is wholly incorporated into a medical training system that thinks in terms of disease models.
