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To determine, if any of the analyzed serum cytokine levels could be used as a potential disease indicator, the diagnostic value of IL-12 (p40) and IL-5 were directly tested in a receiver operating characteristic (Figure 2A, B).
Column 2 provides a description of each disease indicator.
Thus, their detection can serve as an important disease indicator.
The somatic disease indicator was standardized before inclusion in the analyses.
Selective Alzheimer's disease Indicator 1 (or Seladin-1) was first discovered in Alzheimer's disease.
Each data type and disease indicator may have unique characteristics that require modifications of standard data analysis methods.
Similar(39)
Biomarkers may provide diagnostic, prognostic, or burden of disease indicators of OA before radiographic changes become apparent.
Matrix scoring revealed that disease indicators showed strong agreement (W = 0.382 0.659, p < 0.05 p < 0.001) between informant groups.
In the most recent trial (see go.nature.com/2xtrlje), Makoto Akimoto at Mitsubishi Tanabe Pharma, Tokyo, and his colleagues investigated whether edaravone was effective in individuals with early-stage ALS, good respiratory function and other well-defined disease indicators.
It also allows the identification of biological markers, which can serve as early disease indicators and therapeutic markers for the evaluation of treatment effects.
Exploring the longitudinal trajectory of markers related to neurodegeneration is an important task when selecting subjects for treatment in trials and the clinic, in the evaluation of early disease indicators and the monitoring of disease progression.
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CEO of Professional Science Editing for Scientists @ prosciediting.com