Whilst potentially useful for differentiating between benign and malignant breast diseases, implementation is challenging.
The avoidance of toxins, reduction of stress, prevention of somatic diseases, implementation of mental and physical exercises, as well as the use of dietary compounds like antioxidants and supplements can be protective against MCI.
The difficulty of attributing basic science research a large portion of the NIH portfolio to individual diseases complicates implementation of any disease-based allocation process [32]; however, some discrepancies are particularly dramatic.
Molecular techniques can contribute to early diagnosis of cancer, monitoring of minimal residual disease and implementation of effective drug therapies.
The heterogeneous and often cryptic presentation of severe sepsis and septic shock, along with the multifaceted criteria for the definition of this clinical syndrome, pose a particular challenge for fitting requirements to this disease, and implementation could have unintended consequences.
Human engineered heart tissues have potential to revolutionize cardiac development research, drug-testing, and treatment of heart disease; however, implementation is limited by the need to use pre-differentiated cardiomyocytes (CMs).
Among measures for potential eradication of the disease, the implementation of a long term yaws control system with free access to treatment is urgently needed to avoid the further spread of this debilitating disease in the rural Wasolo health zone but also in neighbouring health zones and districts.
Second, the current organisation and resources in PHC centres, aimed almost exclusively at caring for disease, make implementation of such strategies difficult.
Until a vaccine becomes available, public health authorities will need to maintain their focus on surveillance, disease recognition, implementation of control measures, and public education about protective measures.
The main domains used to support judgement, having higher quality scores and weightings, were feasibility, disease burden, implementation and information needs.
