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Ovarian cancer is a heterogeneous disease displaying complex genomic alterations, and consequently, it has been difficult to determine the most relevant copy number alterations with the scale of studies to date.
Potential sources for such biomarkers may be urinary proteins and/or peptides, as these should display significant changes at an early state of disease, displaying initial pathophysiological changes in the kidney [7].
Breast cancer is a heterogeneous disease displaying distinct molecular features and clinical outcome.
NAFLD is a common chronic liver disease displaying a wide spectrum of liver damage, ranging from simple steatosis to steatohepatitis, advanced fibrosis and cirrhosis.
ODDD was first described as a disease displaying craniofacial abnormalities (microphthalmia, dental anomalies, small nose and hypotrichosis), type III syndactyly and missing toe phalanges [ 13].
Macro-AST has to be considered in any healthy individual or patient with a chronic disease displaying an isolated AST-elevation.
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The protozoan parasite Trypanosoma cruzi, agent of Chagas' disease, displays an extensive genetic heterogeneity among strains and isolates.
On biopsy typical disease displays bright polytypic linear GBM staining for IgG by immunofluorescence and diffuse crescentic/necrotizing GN on light microscopy.
In this context, downregulation of the cysH gene in the phoP mutant could contribute to the attenuated phenotype and the protection against disease displayed by this strain.
The patients with active disease displayed many more inflammatory-associated histological changes than patients in remission.
Seventy per cent of the Tollers with signs of disease displayed a positive IIF-ANA test.
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