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Sample sizes were then tested for adequacy in terms of precision at specified levels of confidence for each specific disease combination.
For patients with symptomatic or more extensive disease combination therapy is often used.
Our results highlight the negative impact of this disease combination on HRQL.
In this disease, combination regimens are clearly superior to single-agent ones and they represent the standard of care for patients with good performance status (PS).
In advanced disease, combination chemotherapy with cisplatin or oxaliplatin together with 5FU or capectiabine has palliative benefits (Cunningham et al, 2008).
Despite significant progress, progressive HCC remains an incurable disease; combination of molecular targeted approach will be helpful in management of advanced disease.
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This study used a network analysis to combine results from factor analysis and observed/expected ratios of disease combinations in order to create a pattern-specific disease network.
We investigated the degree of comparability of the prevalence of chronic diseases and disease combinations in the elderly in two databases comparable with regard to diseases included, sex and age of the patients (65 85 years), and cutoff score for case definition.
For that reason, it seams important to discover the underlying structure in the distribution of disease combinations, i.e. which pathways may lead through the labyrinth of multimorbidity.
In accordance with the systemic nature of the disease, combinations are common and in reality, most organs are involved also when not giving symptoms.
Over time, additional chemicals and health end point or disease combinations will be developed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com