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Many of the diseases of interest also have multiple etiologies, and the amount of disease attributed to the specific environmental exposure may be relatively small (the attributable risk).
Parkinson's disease (PD) is a neurodegenerative disease attributed to the loss of midbrain dopaminergic (DA) neurons.
Meanwhile, the number of premature deaths each year due to respiratory illness and disease attributed to household air pollution is increasing.
This paradigm shift provides greater specificity and more accurately measures the global burden of disease attributed to GVHD, and it will facilitate biomarker association studies.
Cancer is a disease attributed to the accumulation of DNA damages due to incapacitation of DNA repair pathways resulting in genomic instability and a mutator phenotype.
Millis, M. P., Bowen, D., Kingsley, C., Watanabe, R. M. & Wolford, J. K. Variants in the plasmacytoma variant translocation gene (PVT1) are associated with end-stage renal disease attributed to type 1 diabetes.
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"Any time I see half a dozen diseases attributed to some exposure, I get very nervous," Dr. Bailar said.
The number of genetically engineered mouse models that have diseases attributed to natural helicobacter infection illustrates the importance of genetic and environmental predisposition in predicting disease outcome.
Still, Jun Chen, a neurobiologist at the University of Pittsburgh in Pennsylvania, is hopeful that the finding could lead to new treatments for diseases attributed to mitochondrial dysfunction.
Strobel added that 80percentt of hospital beds in Fiji are filled by diabetics or people presenting debilitating symptoms from other non-communicable diseases — a range of diseases attributed to diet and lifestyle, including diabetes and obesity, that account for 75percentt of all deaths in the Pacific.
These data are suggestive of a possible effect on human diseases attributed to SNP rs1801133.
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