Sentence examples for disease assumption from inspiring English sources
That is in part because known cases can be compared with selected controls (as opposed to waiting for cases to emerge, which is required by other observational study designs) and in part because of the rare disease assumption, in which OR mathematically becomes an increasingly better approximation of relative risk as disease incidence declines.
Using the rare disease assumption, we combined estimates of odds ratio (OR) and RR [27].
Given the low prevalence of IBD, the OR would approximate the IRR under the rare disease assumption.
Moreover, under rare disease assumption, the OR may be an acceptable approximation of the risk ratio [ 38- 40].
As a consequence the rare disease assumption was not fulfilled in all analyses and the computed odds ratios to some extent overestimated the true RR.
Specificity for advanced neoplasia of gFOBT and FIT was estimated under the rare disease assumption based on the number of false-positive screenees.
This approach requires the rare-disease assumption.
This design allows direct estimation of the risk ratio from a fixed cohort, but does not require any rare-disease assumption.
However, it is difficult to associate these CNVs with the resistance to MD according to our "common variant-disease" assumption, because most of these CNVs were private, rather than population-specific.
Although we have presented results based on a multiplicative disease risk assumption within each sub-phenotype class, applied to directly observed genotypes, the multinomial regression model can easily be extended to incorporate more general disease models by incorporating dominance, and can be utilized with imputed data.
We assumed antibiotic resistant strains would replace sensitive strains, resulting in stable overall prevalence of pneumococcal disease; this assumption is partly supported by several studies in children finding that overall carriage rates of pneumococcus in the nasopharynx remained stable despite serotype replacement with resistant strains after conjugate vaccination [ 19- 21].
