Almost 20 disease affections or types were recorded during clinical visits.
Information on 100% reimbursed severe and costly chronic diseases (affection de longue durée [ALD] [ 11]) is available in the SNIIRAM and coded according to the ICD-10.
Patients were not included if they had a medical history of salivary gland disease or affection, had received external beam radiotherapy to the neck or head, were taking anticholinergic medication, or had dental implants.
Exclusion criteria were ongoing pregnancy, previous incontinence surgery, difficulties passing urine, macroscopic haematuria, known malignancy in the lower abdomen, intermenstrual bleeding, severe psychiatric disorders and neurological disease with affection on sensibility in the legs or lower abdomen.
The combination of IBS, a variety of unexplained somatic symptoms, organic diseases, psychological affection and reduced QoL is common.
Hence, neurological syndromes due to neurovascular and inflammatory causes, which represent the majority in this study and result in the necessity of intensive care only show a limited capacity of complete recovery, whereas diseases without affection of neurons, that is, due to autoimmune causes, recovery may not be limited [ 6].
The question arises whether pSS represents a continuum of patients with different stages of disease/affection of salivary glands or different diseases affecting the salivary gland tissues.
A- and C-cohorts were found to be similar regarding age, disease duration, baseline affection and follow-up rates, and different regarding sample size and gender.
A-cohorts (5 cohorts with 392 patients) were similar to C-cohorts (84 cohorts with 16,167 patients) regarding age, disease duration, baseline affection and follow-up rates.
However, in the original study only three healthy children participated together with 14 children with sickle-cell disease but without known affection of the hips [7].
The patients excluded from our study were; patients with cardiac disease, patients with renal affection, and patients with liver diseases (drug induced, autoimmune disease and viral hepatitis).
