Examples of factors contributing to this are the RNA-seq alignment/assembly being complicated by larger introns, and a higher prevalence of alternative splicing, as discussed in the Background section of this manuscript.
Figure 2 summarises this literature, providing the available elements of a best practice approach for developing national adaptation policy informed by a focus on vulnerable groups in ways that are consistent with the definition of climate vulnerability and the prescriptions of global policy frameworks discussed in the background section of this paper.
As discussed in the background section of the current study, between 1996 and 2002, life expectancy of 25, 35, and 45 year-old men showed a decrease of about 3 to 6 months, while there was no change for 15 year-old men.
As discussed in the background section of this paper, when different communities make naming decisions based on the criteria most relevant to them (gene phylogeny, protein structure, biological function) it is inevitable that multiple names will be used to identify the same entities.
As discussed in the background a comprehensive package of low cost community interventions is developed on the basis of available global and local literature around maternal and neonatal care and survival.
However, as we discussed in the "Background" Section, the quality of this information is not the same across genes.
Although, as discussed in the Background section, a number of genes from various species have been identified in the literature as bimodal or switch-like previously, to our knowledge, the list that we present (1519 genes) is yet the most comprehensive and contains important information on gene regulation in health and disease at the transcript level.
The first, as discussed in the Background, is the known ability of type 1 IFN to activate MAPK/SAPK in mammalian cells.
In sequence analysis, both of the permutation approaches discussed in the background section have the limitation that they disrupt the non-random background distribution of polynucleotides.
Applied to a specific model, these would indeed refer to the reasoning of assumptions, as discussed in the background section.
