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In addition, comparing the results of the three experimental set-ups will help in discriminating effects on gene expression induced by the experimental manipulation (centrifuging, washing and resuspending cells in different media).
We demonstrated that 2DG inhibits PC3 cells growth and had discriminating effects on autophagy regulation based on the different time period of 2DG treatment to control cell survival.
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The BHR mid-level has no discriminating effect on the vertical axis.
A specific principal or secondary diagnosis of COPD or RF has a discriminating effect on the probability of transition to a second admission, remarkably increasing it in patients with Acute Respiratory Failure and in a lesser way in those with Obstructive chronic bronchitis with acute exacerbation.
However, despite its complexity, it is crucial to be able to discriminate effects on feed intake from effects on utilisation of nutrients from ingredients (for growth and other metabolic processes).
In the present study, we have tested a diverse group of chemicals in the EST, applying different exposure durations, in an attempt to discriminate between effects on proliferation and differentiation within the EST protocol.
To discriminate between effects on male courtship behavior through visual, olfactory, and gustatory stimuli, we eliminated their perception in the courting male by mutations that affect single senses but not the processing functions of the central nervous system.
Hence, with this relation the extent of RRP depletion in response to different sucrose concentrations can be used to discriminate between effects on release kinetics and priming.
In complex organisms such as vertebrates, it becomes very difficult to discriminate glucose effects on gene transcription from those related to either insulin or glucagon, whose secretions are regulated by glucose [ 6].
To discriminate the effects on gene expression that are a direct consequence of iron limitation from the effects caused by the increased ROS levels under iron limitation, we compared gene expression under iron limiting conditions in the presence and absence of oxygen in R. sphaeroides.
To discriminate between effects on C/EBPβ-isoform expression by 4E-BPs or S6K1, we used 4E-BP1/4E-BP2 4E-BP1/4E-BP2 4E-BP1/4E-BP2 MEFs (mouse embryonic fibroblasts), or MEFs treatedouble either the S6knockoutitor DG2 or an sh-RNA targeting S6K1.
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