Indeed, the statistical procedure of Section "Weak-sparseness-based time frequency detection for source recovery (multisource selection)" is aimed at detecting time frequency points where signal sources are present, whatever the number of these sources, whereas it is now required to discriminate points where one single source is present from points where multiple sources occur.
Recently, we successfully used a double tandem hybridization strategy in the genesensor chip system to discriminate point mutations in codon 634 of RET oncogene in individuals affected by medullary thyroid carcinoma [ 23].
The following linear model: Yijk = μ + Ti + Gj + (G*T ij + ϵijk, where Ti is the treatment effect (i = irrigated vs. non-irrigated), Gj the family effect (j = "V+" vs. "V-") and (Ti*Gj) is the interaction effect, was used, with P-values < 0.05 considered to identify significant discriminating points.
By contrast, the species were discriminated by point mutations observed at the trnL-F intergenic spacer region.
Item-level analyses revealed generally good distributional properties, inter-rater agreement, discriminating anchor points, and preliminary convergent and discriminant validity.
We used a receiver-operating characteristic (ROC) curve, a plot of the sensitivity versus 1 – specificity, to display the trade-off between true positives and false positives across incremental choices of discriminating cutoff points for glucose disposal rate (9, 10).
What feedback loops can potentially discriminate filaments pointing to the leading edge from filaments pointing backwards?
Using the MI-MB, we could readily discriminate the point mutation-contained p53 from the wild-type one.
The SNP detection is based on the ability to discriminate single point mutations and relies on DNA polymerase with proof reading activity, to extend a primer only when its 3'-end is perfectly complementary to the template [ 25].
"A group of women filed a grievance saying they were being discriminated against, and pointed to me as the person who was getting the benefits," Villaraigosa recalled.
