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For both treatments we gave centres discretion to start azathioprine or 6-mercaptopurine at therapeutic doses in week 4. We asked them to eliminate steroids by week 12 in patients who remained well but to reinstate them in patients who became symptomatic.
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Because this is the last trip to town for the Red Sox, the umpires had discretion over when to start and stop play.
We hope parliament will now use its discretion and support sensible measures to start to comply with, and implement, the judgment.
The decision whether to start bisphosphonates was at the discretion of the treating physician.
The decision to treat conservatively or to start RRT was at the discretion of the responsible physician, taking into account the rules of good clinical practice in this field.
The decision to start RRT was left at the discretion of the attending ICU physicians.
Legislatures should go further and require judges to start with alimony formulas, and then apply discretion.
Prescription of DrotAA followed national guidelines but the decision to start the drug was left at the discretion of the attending physician.
However, this treatment was not protocolized and the decision to start HFOV was, at times, based on clinical discretion.
In our study, the decision whether to start with Aflibercept or Ranibizumab was fully at the discretion of the treating physician and we expected that equipoise was present.
To start, the City Council's budget process needs a lot less discretion and a lot more transparency.
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