Among the parallel-group trials, RRT was discontinued at the clinicians' discretion [ 21- 25, 27, 29] 29], after a fixed duration [ 24, 28], or when protocol-defined criteria were met [ 26, 30].
Specifically, all U.S. states have laws either requiring interlocks for certain offenders or allowing courts to order interlocks at their discretion [12].
Administration of additional 40UI of Botox® was allowed, in line with the PREEMPT modified "follow the pain" paradigm, at the injector's discretion [19].
Second problem, there is a footnote that allows the substitution of DSM-IV for DSM-5 diagnosis -- again at the clinician's discretion (p51).
Reasons for not completing chemotherapy were toxicity (n=3), patient refusal (n=1), or physician discretion (n=2).
Subsequently, patients received adjuvant chemotherapy at investigator discretion (n=37; 48.7%) and/or hormonotherapy with tamoxifen (n=34; 44.7%).
Lower volumes could be chosen at the supervisor's discretion (200 ml or even 100 ml).
Reasons for not completing radiation therapy were radiation oesophagitis (n=3), radiation pneumonitis (n=1), patient refusal (n=1), or physician discretion (n=1).
A bone graft substitute (Norian SRS), also inserted percutaneously, was used at the surgeons' discretion (2 patients).
Self-assessment frequency varied by intervention occurring weekly (74, 76, 83), monthly (76), quarterly (82, 84), or at the provider's discretion (82).
