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Discrete expression pattern of Shh versus Ihh in the developing skull indicates some possible differences in functions.
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Given the functions and discrete expression patterns of many known members, it seems likely that this superfamily, including the novel proteins identified here, could provide the requisite specificity of cellular interactions to mediate a large number of selective connectivity decisions.
Many of the ARF/ Aux/IAA family of genes had discrete expression patterns for a single stage of fruit development.
They transformed the quantitative expression levels into discrete expression patterns (expressed or unexpressed).
Four genes, OsAGO14, OsRDR3, OsRDR4 and OsDCL3a, showing discrete expression patterns were selected for validation of microarray expression profiles by QPCR analysis.
Alterations in regulatory elements could produce discrete expression patterns that, together, would recapitulate the more complex expression pattern of the ancestral gene [ 6].
The Tensin family is composed of four members: Tensin1, Tensin2, Tensin3 and Tensin4 (TNS2, TNS3, TNS4, TNS4) each with discrete expression patterns in the human body [1], [2].
Eight genes showing discrete expression patterns were selected for validation by QPCR analysis.
Figure 3C also shows the correlation between the discrete and the continuous expression pattern of the species downstream of the feedback loops at each time point 0 < t < 100.
The proteomic profiling of muscle plasticity has established discrete changes in the abundance and expression pattern of contractile proteins and metabolic enzymes during myogenesis and fibre maturation, as well as in response to enhanced neuromuscular activity, disuse-associated atrophy or chronic electrostimulation [ 18].
Global identification of developmental enhancers in the human genome, in tandem with many other studies, strongly support a modular regulatory architecture for many developmental genes, in which an array of multiple discrete, partially redundant cis-regulatory elements interact to define the total expression pattern of a particular gene (Fig. 1).
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