Sentence examples for discrete cell types that from inspiring English sources

Thus, transgenes that create novel associations between tissue-specific silencers and more diffusely expressed activator elements may be a useful strategy for labeling and manipulating discrete cell types that are otherwise difficult to demarcate.

This result was further refined by Chan et al. by demonstrating the formation of multicellular bone tissue at other ectopic sites and by unravelling routes of differentiation from a discrete progenitor subpopulation to cell types that either contribute to bone, cartilage or haematopoiesis-supportive stroma within the new bone organ (Ref. 21).

In addition, whether hemangioblastomas form from an embryologically arrested "hemangioblast" stem cell that subsequently differentiates into the discrete constituent cell types that support the architecture of this vascular tumor [ 1, 23- 25] is unclear.

Optogenetics has revolutionized neuroscience by providing means to control cell signaling with spatiotemporal control in discrete cell types.

Porifera (sponges) lack organs and nervous systems and possess a limited number of discrete cell types [2].

Drosophila muscles are formed through the fusion of two discrete cell types: founder cells (FCs) and fusion-competent myoblasts (FCMs).

It is very difficult to map the functional connectivity of discrete cell types in the intact mammalian brain during behavior.

How this operates within the nervous system and whether it might be a distinguishing feature of NF-κB activation by discrete stimuli and in distinct cell types remains unknown.

Surprisingly, this domain is subdivided into discrete regions, giving rise to lens domains that comprise functionally distinct cell types (Greiling and Clark, 2009; Lovicu and McAvoy, 2005).

For the functional analysis of different cell populations, we selected cells with highest level of EpCAM (EpCAM+) and lowest level of EpCAM (EpCAM−) and sorted three distinct cell types (CD34−/EpCAM−, CD34+/EpCAM−, CD34−/EpCAM+) and a fourth smaller and less discrete group of cells that were CD34+/EpCAM+ (figure 4B).

Comparison of interactions between cell types revealed that enhancer-promoter interactions were highly cell-type-specific.