Sentence examples for discrete alterations from inspiring English sources

We conclude that discrete alterations in CMI may be induced by HDBR in selected individuals.

Knockout of single HDAC family members in mice produces a variety of phenotypes ranging from early embryonic death to viable animals with only discrete alterations, indicating that potential side effects of HDAC inhibitors depend on the selectivity of the compounds.

Furthermore, we highlight DTI as a technical support for the exploration of such discrete alterations.

We cannot however exclude that DNA methylation changes at single or selected CpGs within promoters may lead to transcriptional perturbations as the MeDIP-array approach is likely not sensitive enough to detect very discrete alterations.

However, more discrete alterations cannot be discarded and additional experiments using germ-free animals and/or molecular methods for bacterial detection are required to further explore the relationship between Card15/Nod2 and the normal gut flora.

Two novel discrete alterations identified by array CGH were verified by fluorescence in situ hybridization.

A bony tubercle was identified at the anterior portion of the lateral epicondyle of some of the evaluated lateral epicondyles (61%) as a discrete alteration in the epicondyle surface.

If a PCR product did not show any discrete alteration on the gel, the mutant was classified as one containing a point mutation with either a base substitution or a frameshift causing no alteration in the size of the gene product.

The technique should allow detection of large but also discrete mucosal alterations.

A signature of 128 miRNAs enabled the characterization of lymphoma neoplasms, reflecting the lymphoma type, cell of origin and/or discrete oncogene alterations.

Furthermore, discrete degenerative alterations of the aortic and mitral valve could be shown, but there was no evidence of inherent structural or functional cardiac abnormalities.