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Methodological limitations of the extant literature contribute to the discrepancy in study results and make it challenging to draw definitive conclusions.
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Andrew Krystal, a Duke University psychiatrist and consultant to pharmaceutical companies like Sepracor, Lunesta's manufacturer, acknowledges an apparent discrepancy in studies between small, objectively recorded improvements and the large percentage of subjects who end up feeling that a pill alleviated their insomnia.
We illustrated the discrepancies in study protocols among researchers in animal studies and emphasized the need to develop and follow a set of generally accepted standardized guidelines.
These discrepancies in study results may be ascribable to differences in study design, patient age, intervention duration, assessment tool sensitivity, and LCPUFA sources.
Discrepancies in study findings about the efficacy of education for effecting positive attitudes of student nurses toward impaired nurses may be related to the length and type of the education.
Discrepancies in study design, inclusion criteria, statistical methodology, and the varying definitions of both clinical and microbiological endpoints between the published studies, make it difficult to compare them, as well as to determine which regimen may be the most appropriate for patients with diabetic foot infection.
Discrepancies in study inclusion were resolved by consensus (M.G.K.).
Any disagreements or discrepancies in study selection were moderated by consensus.
However, conflicting data remains from the most recent randomized controlled trial, and even though this can be related to discrepancies in study design and outcome reporting, more trials are needed in order to ascertain the usefulness of CHG-WC bathing in the ICU. Figure 1 Overall impact of CHG-WC in HABS/CLABSI.
Discrepancies in study quality were examined as potential contributors to inter-study heterogeneity.
Major inconsistencies included discrepancies in study objective and/or hypothesis, study design, primary outcome measures, sample size, statistical analysis, results, and standard deviations/confidence intervals.
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