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When there are guidelines on the same question of interest produced by different organizations, discrepancies in recommendations may generate confusion.
We chose this example because we were aware of the startling discrepancies in recommendations from different reviews addressing the question.
The more rigorous guidelines showed discrepancies in recommendations and grading that reflected different approaches to the use of evidence in guideline development.
An article by Ray et al. noted there are also discrepancies in recommendations across guidelines, potentially contributing to low adherence rates [ 2, 4, 5].
This is reflected in the published literature, particularly in the rheumatological literature and can lead to discrepancies in published recommendations.
These findings suggest that differences in decision criteria and/or the priorities assigned to them account for some, if not all, of the discrepancies in current recommendations regarding the management of adult patients with a sore throat.
More likely, it is due to discrepancies in national recommendations, different health care systems, different treatment traditions, different culture, different patient expectations or different impact of marketing by pharmacies and pharmaceutical companies.
The different antibiotic prescribing rates between countries may be due to discrepancies in national recommendations, different health care systems, different treatment traditions, different culture, different patient expectations or different impact of marketing by pharmacies and pharmaceutical companies.
There appears to be a considerable discrepancy between recommendations and sedation practice.
In steps two to four, there is a big discrepancy between the recommendations by ECHA and the actual situations in the EU and SA, illustrating that PCPs RC is not in line with ECHA recommendations.
For example, a systematic review and cumulative meta-analysis (continually updating the meta-analysis with results from more recent clinical trials) in cardiovascular medicine found discrepancies between recommendations by clinical experts and meta-analytic evidence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com