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A search of sequences from non-assembled bins did not detect the proposed missing sequence; likewise, no discrepancies in coverage could be found for the region proposed to contain the missing sequences.
Despite some discrepancies in coverage across samples, the high read coverage provided by the Miseq ensured sufficient coverage for each individual.
For example, there are discrepancies in coverage for home and community care depending on their recognition as a professionally-delivered service (e.g., delivered by a physician in a hospital versus delivered by a home care worker in the community) [ 23].
Such discrepancies in coverage are manifested in the entropy rate: the pseudo-human genome has entropy rate equal to the maximal value log2 4 or 2 bits per symbol and bounds from above the entropy rate of the human genome.
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Still, the discrepancy in coverage reflects a certain hypocrisy.
This discrepancy in coverage counts could be attributed to a different treatment of quality scores in read counting and/or different default parameters among the callers, since we applied identical quality thresholds to the data.
Some of this discrepancy in coverage rates may have resulted from a selection bias from our convenience survey of individuals who already had access to health services due to their child's diagnosis.
A limitation of our study is that we did not assess if structural variation, such as common and rare copy number variants (CNVs), contribute to the discrepancy in coverage when analyzing a small subset of genes especially in the presence of population specific CNVs.
The story of the fallacy of coverage is made up of five theme areas of evidence - timeliness of immunization, social and gender inequities, vaccine efficacy, understanding demand side issues to tailor interventions, and national data sets masking actual district level coverage rates - that reveal the discrepancies in immunization coverage rates and the reasons behind these discrepancies.
The story of the fallacy of coverage is made up of five theme areas of evidence that reveals the discrepancies in immunization coverage rates and the reasons behind these discrepancies.
The paper first reviews the standard, then compares the standard with ASHRAE Standard 90.1-2004 to identify discrepancies in code coverage and stringency, and recommends some energy conservation measures that can be evaluated in the design of public buildings to achieve energy savings beyond the standard.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com